If you want to cheat, go to http://www.wordsmith.org/anagram/advanced.html. Set 'Minimum number of letters in each word' to '5' or '6' depending on the word, select 'Print candidate word list only', enter the word under 'Input (word/phrase to be anagrammed)' and voila.

I got the definitions from http://www.dictionary.com. And if you're into looking up definitions, see InternetExplorerContextMenuTrick

• Anise - An annual, aromatic Mediterranean herb (Pimpinella anisum) in the parsley family, cultivated for its seedlike fruits and the oil obtained from them and used to flavor foods, liqueurs, and candies.
• Finis - The end; the conclusion: setbacks that wrote finis to our venture
• Ketch - A two-masted fore-and-aft-rigged sailing vessel with a mizzenmast stepped aft of a taller mainmast but forward of the rudder.
• Dropsy - Edema. No longer in scientific use.(An excessive accumulation of serous fluid in tissue spaces or a body cavity.)
• Zinnia - Any of various plants of the genus Zinnia, native to tropical America, especially Z. elegans, widely cultivated for its showy, rayed, variously colored flower heads.Also called regionally old maid, old maid flower

-- MattWalsh - 08 Jan 2002